Who Really Knows how to Die?

Nobody really knows how to perform endoscopic necrosectomy

The advent of lumen-apposing metal stents (LAMSs) as a tool in endoscopic ultrasound (EUS) has had what can only be called a transformative effect on EUS‐guided drainage of pancreatic fluid collections (PFCs) including pseudocysts and, more importantly, walled‐off pancreatic necrosis.[1-6] These procedures are being performed at more centers and in much greater numbers than ever before. Older t...

Who knows how to treat systemic light chain amyloidosis?

A rarely noted aspect of the era of novel agents and explosive new knowledge in the clonal plasma cell diseases is how short the half-life of relevant information has become, and how this churning has challenged clinical thinking.[1] We may, at times, lose sight of a core concept in the treatment of patients with clonal plasma cell diseases: that baseline risk to patient survival derives from t...

Who Cares How Congress Really Works?

Who knows this patient?

. . . in my view the pendulum has over swung with the stringent new ACGME residency work-hour restrictions. I do not believe that the challenges to continuity of care are of benefit to either patients or trainees. We walked down the hall at a brisk pace, challenged with the task of seeing all the patients before our time for rounds expired. Upon reaching the sought-after room, I inquired “who k...

How George Soros Knows What He Knows

In its traditional formulation as an explanatory principle, reflexivity means that any object of thought contains in itself the thinking activity that generates it. Applying the concept of reflexivity to the question of financial markets valuation, Soros concludes that economic reality is actively shaped by the perceptions of market participants. This leads him to a theory of investment radical...